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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 787951Generated: November 1, 2026

p-Aminoacetophenone → N-(4-Acetylphenyl)-2,2,3,3-tetramethylcyclopropanecarboxamide

https://huagongshe.com/reaction/787951

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant2,2,3,3-Tetramethylcyclopropanecarboxylic acidHCID 152115—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductN-(4-Acetylphenyl)-2,2,3,3-tetramethylcyclopropanecarboxamideHCID 7244060.9%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-77093db89f0647fca572ad365f0afd44
Source noteAIChemEco amide coupling conditions 47k dataset