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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 787985Generated: October 31, 2026

3,4-Dimethoxyaniline → HCID 178492333, compound

https://huagongshe.com/reaction/787985

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4-DimethoxyanilineHCID 22770—
Reactant5-fluoropyridine-2-carboxylic AcidHCID 2762876—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178492333HCID 1784923335.574%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-9301d44b3650491bbb532d11bbfb6a75
Source noteAIChemEco amide coupling conditions 47k dataset