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HRID78804

反应详情

EQUATION

反应方程式

HRID 78804 的结构方程式

REACTANTS

反应物

2
结构：CC1(C)OC[C@H](CON)O1
HCID11298047

O-{[(4R)-2,2-Dimethyl-1,3-dioxolan-4-yl]methyl}hydroxylamine

C6H13NO3

结构：O=C(O)c1ccnc(Cl)c1Nc1ccc(I)cc1F
HCID57649634

未命名化合物

PRODUCTS

生成物

1
结构：CC1(C)OC[C@H](CONC(=O)c2ccnc(Cl)c2Nc2ccc(I)cc2F)O1
HCID57649632

未命名化合物

PROCEDURE

实验过程

2-Chloro-N-{[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]methoxy}-3-(2-fluoro-4-iodo-phenylamino)-isonicotinamide was synthesized according to the procedure for General Method 1, outlined above, starting with 0.2 mmol of 2-chloro-3-(2-fluoro-4-iodo-phenylamino)-isonicotinic acid and 0.3 mmol of O-{[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl}-hydroxylamine LC/MS [9.19 min; 522 (M+1)].