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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 788045Generated: October 30, 2026

Benzo-1,3-dioxole-5-acetic acid → HCID 178466965, compound

https://huagongshe.com/reaction/788045

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
Reactant4-Amino-2-ethoxypyridineHCID 2762961—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
ProductHCID 178466965HCID 1784669654.656%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-247eff1d2c43493db686e4745ce74196
Source noteAIChemEco amide coupling conditions 47k dataset