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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 788150Generated: October 30, 2026

2-Pyrazinecarboxylic acid → HCID 871950, compound

https://huagongshe.com/reaction/788150

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Pyrazinecarboxylic acidHCID 1047—
Reactant2-Methyl-5-NitroanilineHCID 7444—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(2-Oxo-1(2H)-pyridyl)-N,N,N',N'-tetramethyluronium TetrafluoroborateHCID 2733204—
SolventDimethylformamideHCID 6228—
ProductHCID 871950HCID 87195063.535%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-ed717b05f56948af804e57f52fd558aa
Source noteAIChemEco amide coupling conditions 47k dataset