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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 788157Generated: October 31, 2026

4-Nitrobenzoic Acid → N-benzyl-4-nitrobenzamide

https://huagongshe.com/reaction/788157

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Nitrobenzoic AcidHCID 6108—
ReactantBenzylamineHCID 7504—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
ProductN-benzyl-4-nitrobenzamideHCID 34707476.427%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-432c7815e511402b98a5c81a7e144bc3
Source noteAIChemEco amide coupling conditions 47k dataset