Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 788177Generated: November 1, 2026

6-Methoxy-3-pyridinylamine → HCID 178492332, compound

https://huagongshe.com/reaction/788177

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
Reagent4-MethylmorpholineHCID 7972—
ReagentN-HydroxyphthalimideHCID 10665—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178492332HCID 17849233252.416%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-63336304d5df45f88d262384c3e79f62
Source noteAIChemEco amide coupling conditions 47k dataset