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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 78820Generated: October 30, 2026

7-Chloro-4-hydrazinylquinoline → N'-(7-chloroquinolin-4-yl)-3-[(2-fluoro-4-iodophenyl)amino]isonicotino-hydrazide

https://huagongshe.com/reaction/78820

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-Chloro-4-hydrazinylquinolineHCID 32109—
Reactant3-((2-Fluoro-4-iodophenyl)amino)isonicotinic acidHCID 59026791—
ProductN'-(7-chloroquinolin-4-yl)-3-[(2-fluoro-4-iodophenyl)amino]isonicotino-hydrazideHCID 11519423—

Reaction Steps

N′-(7-chloroquinolin-4-yl)-3-[(2-fluoro-4-iodophenyl)amino]isonicotino-hydrazide was synthesized according to the procedure for General Method 1, outlined above, starting with 0.33 mmol of 3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid (intermediate 1) and 0.50 mmol of 7-chloroquinolin-4-yl-hydrazine. LC/MS [7.69 min; 534 (M+1)]

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08841459B2
Source datasetuspto-grants-2014_09
ORD IDord-754110a31a824d7681107f753f9c7861
Source noteuspto-grants-2014_09