HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclobutylamine → N-(cyclobutyl)-3-[(2-fluoro-4-iodophenyl)amino]isonicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclobutylamine | HCID 75645 | — |
| Reactant | 3-((2-Fluoro-4-iodophenyl)amino)isonicotinic acid | HCID 59026791 | — |
| Product | N-(cyclobutyl)-3-[(2-fluoro-4-iodophenyl)amino]isonicotinamide | HCID 11531663 | — |
Reaction Steps
N-(cyclobutyl)-3-[(2-fluoro-4-iodophenyl)amino]isonicotinamide was synthesized according to the procedure for General Method 1, outlined above, starting with 0.34 mmol of 3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid (intermediate 1) and 0.42 mmol of cyclobutylamine. LC/MS [9.86 min; 412 (M+1)]
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08841459B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-720e84359df4462da2333b9203e63c1f |
| Source note | uspto-grants-2014_09 |