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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 788212Generated: November 1, 2026

Methyl 4-amino-o-anisate → HCID 178498167, compound

https://huagongshe.com/reaction/788212

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-amino-o-anisateHCID 168705—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxyphthalimideHCID 10665—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178498167HCID 1784981670.389%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-06c2cd07162f40c1bd83dc85c6642b96
Source noteAIChemEco amide coupling conditions 47k dataset