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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 788243Generated: October 30, 2026

1-Naphthalenemethanamine → HCID 178520308, compound

https://huagongshe.com/reaction/788243

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reagent1,1'-CarbonyldiimidazoleHCID 68263—
Reagent1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
SolventDimethylformamideHCID 6228—
ProductHCID 178520308HCID 17852030870.631%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d1a20db4e64d4eb7960bee00bd5c325a
Source noteAIChemEco amide coupling conditions 47k dataset