HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Amino-1-propanol → 2-Bromo-5-(2-fluoro-4-iodo-phenylamino)-N-(3-hydroxy-propyl)-isonicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Amino-1-propanol | HCID 9086 | — |
| Reactant | 2-Bromo-5-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid | HCID 57649649 | — |
| Product | 2-Bromo-5-(2-fluoro-4-iodo-phenylamino)-N-(3-hydroxy-propyl)-isonicotinamide | HCID 11569493 | — |
Reaction Steps
2-Bromo-5-(2-fluoro-4-iodo-phenylamino)-N-(3-hydroxy-propyl)-isonicotinamide was synthesized according to General method 3, starting with 145 mg (0.33 mmol) of 2-bromo-5-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid and 62 mg (0.82 mmol) of 3-Amino-propan-1-ol. LC/MS: [9.15 min, 494, 496]
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08841459B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-b4119bee93e4472db3a60d0805976d02 |
| Source note | uspto-grants-2014_09 |