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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 78832Generated: October 30, 2026

4-Iodoaniline → 3-(4-Iodophenyl)amino-isonicotinic acid

https://huagongshe.com/reaction/78832

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-IodoanilineHCID 10893—
Reactant2-Fluoroisonicotinic acidHCID 345360—
Product3-(4-Iodophenyl)amino-isonicotinic acidHCID 11709852—

Reaction Steps

3-(4-iodo-phenylamino)-isonicotinic acid was synthesized according to the procedure for General Method 1 and as Intermediate 1 by reacting 1.4 mmol of 4-iodoaniline with 2.8 mmol of 2-fluoro-isonicotinic acid LC/MS [6.29 min; 341 (M+1)].

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08841459B2
Source datasetuspto-grants-2014_09
ORD IDord-bfde92079728477cbf54f9256d2d1805
Source noteuspto-grants-2014_09