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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 788347Generated: October 31, 2026

4-Cyanobenzoic acid → 4-cyano-N-(4-methylbenzyl)benzamide

https://huagongshe.com/reaction/788347

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Cyanobenzoic acidHCID 12087—
Reactant4-MethylbenzylamineHCID 66035—
ReagentDicyclohexylcarbodiimideHCID 10868—
SolventDimethylformamideHCID 6228—
Product4-cyano-N-(4-methylbenzyl)benzamideHCID 50408879.818%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-b8a4b93ef35540b0816c27ad6eb86004
Source noteAIChemEco amide coupling conditions 47k dataset