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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 78836Generated: October 25, 2026

3-Chloropropylamine → N-(3-chloropropyl)-3-[(2-fluoro-4-iodophenyl)amino]isonicotinamide

https://huagongshe.com/reaction/78836

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-ChloropropylamineHCID 84629—
Reactant3-((2-Fluoro-4-iodophenyl)amino)isonicotinic acidHCID 59026791—
ProductN-(3-chloropropyl)-3-[(2-fluoro-4-iodophenyl)amino]isonicotinamideHCID 11633443—

Reaction Steps

N-(3-chloropropyl)-3-[(2-fluoro-4-iodophenyl)amino]isonicotinamide was synthesized according to the procedure for General Method 1, outlined above, starting with 1 mmol of 3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid (intermediate 1) and 1.3 mmol of 3-chloropropylamine. LC/MS [9.24 min; 434 (M+1)]

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08841459B2
Source datasetuspto-grants-2014_09
ORD IDord-0c4972c9cd1d40a3b4cdf49c7fe3c4b3
Source noteuspto-grants-2014_09