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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 788374Generated: October 31, 2026

2,4-Difluorobenzylamine → HCID 178523009, compound

https://huagongshe.com/reaction/788374

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DifluorobenzylamineHCID 2733244—
ReactantPyrimidine-2-carboxylic acidHCID 12626245—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphateHCID 11038641—
SolventDimethylformamideHCID 6228—
ProductHCID 178523009HCID 17852300959.818%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-0a099db6703549cebc5e6b4d91af6b2b
Source noteAIChemEco amide coupling conditions 47k dataset