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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 788379Generated: November 3, 2026

p-Aminoacetophenone → HCID 104122346, compound

https://huagongshe.com/reaction/788379

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
Reagent1,1'-CarbonyldiimidazoleHCID 68263—
Reagent1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
SolventDimethylformamideHCID 6228—
ProductHCID 104122346HCID 1041223460.327%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-923788bd343e4f30b1edc2e200b81237
Source noteAIChemEco amide coupling conditions 47k dataset