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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 78841Generated: October 26, 2026

p-Methylphenethylamine → 3-[(2-fluoro-4-iodophenyl)amino]-N-[2-(4-methylphenyl)ethyl]isonicotinamide

https://huagongshe.com/reaction/78841

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-MethylphenethylamineHCID 76751—
Reactant3-((2-Fluoro-4-iodophenyl)amino)isonicotinic acidHCID 59026791—
Product3-[(2-fluoro-4-iodophenyl)amino]-N-[2-(4-methylphenyl)ethyl]isonicotinamideHCID 11712599—

Reaction Steps

3-[(2-fluoro-4-iodophenyl)amino]-N-[2-(4-methylphenyl)ethyl]isonicotinamide was synthesized according to the procedure for General Method 1, outlined above, starting with 0.54 mmol of 3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid (intermediate 1) and 0.62 mmol of 2-(4-methylphenyl)ethylamine. LC/MS [10.25 min; 476 (M+1)]

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08841459B2
Source datasetuspto-grants-2014_09
ORD IDord-3f6b4b711f0e4921ac7e990d290ca0be
Source noteuspto-grants-2014_09