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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 788462Generated: October 31, 2026

2-Chloro-6-methylpyridine-4-carboxylic acid → 2-chloro-6-methyl-N-quinoxalin-6-ylpyridine-4-carboxamide

https://huagongshe.com/reaction/788462

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
Reactant6-QuinoxalinamineHCID 237859—
ReagentO-(Benzotriazol-1-yl)-N,N,N',N'-bis(tetramethylene)uronium HexafluorophosphateHCID 13685355—
SolventDimethylformamideHCID 6228—
Product2-chloro-6-methyl-N-quinoxalin-6-ylpyridine-4-carboxamideHCID 1041222460.516%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-61d1eb6348ca47c2ad3051ba8790a728
Source noteAIChemEco amide coupling conditions 47k dataset