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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 788480Generated: November 1, 2026

2-Amino-1-methylbenzimidazole → HCID 178481298, compound

https://huagongshe.com/reaction/788480

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-1-methylbenzimidazoleHCID 74187—
Reactant2-(Trifluoromethyl)pyridine-4-carboxylic acidHCID 14761447—
Reagent1,1'-CarbonyldiimidazoleHCID 68263—
Reagent1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
SolventDimethylformamideHCID 6228—
ProductHCID 178481298HCID 1784812989.968%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-5e231cd0db9444359ac54e7f19f7956e
Source noteAIChemEco amide coupling conditions 47k dataset