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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 78852Generated: October 30, 2026

3-Methoxyaniline → 3-[(2-fluoro-4-iodophenyl)amino]-N-(3-methoxyphenyl)isonicotinamide

https://huagongshe.com/reaction/78852

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-MethoxyanilineHCID 10824—
Reactant3-((2-Fluoro-4-iodophenyl)amino)isonicotinic acidHCID 59026791—
Product3-[(2-fluoro-4-iodophenyl)amino]-N-(3-methoxyphenyl)isonicotinamideHCID 11648339—

Reaction Steps

3-[(2-fluoro-4-iodophenyl)amino]-N-(3-methoxyphenyl)isonicotinamide was synthesized according to the procedure for General Method 1, outlined above, starting with 0.31 mmol of 3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid (intermediate 1) and 0.46 mmol of 3-methoxyaniline. LC/MS [6.40 min; 464 (M+1)]

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08841459B2
Source datasetuspto-grants-2014_09
ORD IDord-595263b4baee4c7b84487c50ac794b51
Source noteuspto-grants-2014_09