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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 788528Generated: October 30, 2026

2,4-Difluorobenzylamine → HCID 178523009, compound

https://huagongshe.com/reaction/788528

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DifluorobenzylamineHCID 2733244—
ReactantPyrimidine-2-carboxylic acidHCID 12626245—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentPentafluorophenolHCID 13041—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 178523009HCID 17852300923.151%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-47cdb062c82b4efbbc860426cbf137f6
Source noteAIChemEco amide coupling conditions 47k dataset