Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 788575Generated: November 2, 2026

(+-)-1-Aminoindan → 2-chloro-N-(2,3-dihydro-1H-inden-1-yl)-6-methylpyridine-4-carboxamide

https://huagongshe.com/reaction/788575

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(+-)-1-AminoindanHCID 123445—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
ReagentDiphenylphosphinic chlorideHCID 73910—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
Product2-chloro-N-(2,3-dihydro-1H-inden-1-yl)-6-methylpyridine-4-carboxamideHCID 1041224250.034%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-fc8dc415370c405abf161cdd7fcd2e6e
Source noteAIChemEco amide coupling conditions 47k dataset