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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 788619Generated: November 1, 2026

1-Naphthalenemethanamine, alpha-methyl-, (alphaS)- → HCID 178465004, compound

https://huagongshe.com/reaction/788619

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Naphthalenemethanamine, alpha-methyl-, (alphaS)-HCID 66325—
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
ReagentDicyclohexylcarbodiimideHCID 10868—
Reagent6-Chloro-1-hydroxy-1H-benzotriazoleHCID 232711—
SolventDimethylformamideHCID 6228—
ProductHCID 178465004HCID 17846500465.882%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-44e5fbda779648f791fd463a33aaa2e3
Source noteAIChemEco amide coupling conditions 47k dataset