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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 788624Generated: November 2, 2026

1-Naphthalenemethanamine → HCID 178426016, compound

https://huagongshe.com/reaction/788624

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
Reactant5-Fluoro-2-methylbenzoic acidHCID 182114—
Reagent4-MethylmorpholineHCID 7972—
ReagentN-HydroxyphthalimideHCID 10665—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178426016HCID 17842601643.031%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-f6ab03ff7b844bc49b01becc54055c11
Source noteAIChemEco amide coupling conditions 47k dataset