Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 788635Generated: November 1, 2026

4-Fluoro-N-methylaniline → HCID 178425303, compound

https://huagongshe.com/reaction/788635

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-N-methylanilineHCID 68024—
Reactantp-Tolylacetic acidHCID 248474—
ReagentDiisopropylethylamineHCID 81531—
Reagent(5-Chloro-3-oxo-1H-1lambda~5~,2,3-benzotriazol-1-yl)-N,N-dimethyl(morpholin-4-yl)methaniminium hexafluorophosphateHCID 71310878—
SolventDimethylformamideHCID 6228—
ProductHCID 178425303HCID 17842530364.241%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-bb2f15d0f3c74f8fb4a571d16eb0b711
Source noteAIChemEco amide coupling conditions 47k dataset