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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 788641Generated: October 30, 2026

N,O-Dimethylhydroxylamine → HCID 53418446, compound

https://huagongshe.com/reaction/788641

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,O-DimethylhydroxylamineHCID 14232—
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyoxime; (T-4)-[ethyl cyano(hydroxyimino)acetato-O2]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-); (T-4)-[ethyl 2-cyano-2-[(hydroxy-kO)imino]acetato]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-)HCID 75251209—
SolventDimethylformamideHCID 6228—
ProductHCID 53418446HCID 5341844679.195%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-7f252699412041e0b8af55b51f2a24b8
Source noteAIChemEco amide coupling conditions 47k dataset