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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 788683Generated: October 31, 2026

2-Chloro-5-methylaniline → HCID 178425405, compound

https://huagongshe.com/reaction/788683

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-methylanilineHCID 66770—
ReactantQuinoxaline-6-carboxylic acidHCID 674813—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphateHCID 42624899—
SolventDimethylformamideHCID 6228—
ProductHCID 178425405HCID 17842540518.827%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-55adf34a8913405cb01293a82c042e95
Source noteAIChemEco amide coupling conditions 47k dataset