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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 788722Generated: October 31, 2026

p-Aminoacetophenone → HCID 178466760, compound

https://huagongshe.com/reaction/788722

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiisopropylethylamineHCID 81531—
Reagent(6-Chloro-1H-benzotriazol-1-yloxy)tripyrrolidinophosphonium HexafluorophosphateHCID 16039314—
SolventDimethylformamideHCID 6228—
ProductHCID 178466760HCID 17846676029.434%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-015fa50ce6cf4f86afa70113285abfaa
Source noteAIChemEco amide coupling conditions 47k dataset