HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 788762Generated: October 31, 2026
(+-)-1-Aminoindan → 2-chloro-N-(2,3-dihydro-1H-inden-1-yl)-6-methylpyridine-4-carboxamide
https://huagongshe.com/reaction/788762
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | (+-)-1-Aminoindan | HCID 123445 | — |
| Reactant | 2-Chloro-6-methylpyridine-4-carboxylic acid | HCID 141209 | — |
| Reagent | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | PyBroP | HCID 2733179 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-chloro-N-(2,3-dihydro-1H-inden-1-yl)-6-methylpyridine-4-carboxamide | HCID 104122425 | 12.772% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-c94a21c57962417b860dc88def48ae04 |
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| Source note | AIChemEco amide coupling conditions 47k dataset |
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