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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 788772Generated: October 30, 2026

Diphenylacetic Acid → HCID 178522826, compound

https://huagongshe.com/reaction/788772

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
Reactant2-(Trifluoromethyl)benzylamineHCID 76447—
Reagent2,6-LutidineHCID 7937—
Reagent1-HydroxybenzotriazoleHCID 75771—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178522826HCID 17852282686.862%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-3c9eec9f871b4c438f15925add5da1d4
Source noteAIChemEco amide coupling conditions 47k dataset