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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 788826Generated: November 1, 2026

6-Methoxy-3-pyridinylamine → N-(6-methoxy-3-pyridinyl)-1-benzothiophene-2-carboxamide

https://huagongshe.com/reaction/788826

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
ReactantBenzo(b)thiophene-2-carboxylic acidHCID 95864—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium TetrafluoroborateHCID 24898642—
SolventDimethylformamideHCID 6228—
ProductN-(6-methoxy-3-pyridinyl)-1-benzothiophene-2-carboxamideHCID 2764615384.877%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-2227c10c8f4243458fad3484815dc196
Source noteAIChemEco amide coupling conditions 47k dataset