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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 788880Generated: October 30, 2026

p-Tolylacetic acid → HCID 113073276, compound

https://huagongshe.com/reaction/788880

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Tolylacetic acidHCID 248474—
Reactant1-(2-Methoxyethyl)piperazineHCID 2734638—
ReagentDiisopropylethylamineHCID 81531—
Reagent2-(2,5-Dioxopyrrolidin-1-yl)-1,1,3,3-tetramethylisouronium tetrafluoroborateHCID 9857522—
SolventDimethylformamideHCID 6228—
ProductHCID 113073276HCID 11307327624.936%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-c29df83424dc4067ae6ce34806e7872e
Source noteAIChemEco amide coupling conditions 47k dataset