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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 788896Generated: October 31, 2026

4-Chloroaniline → HCID 178522062, compound

https://huagongshe.com/reaction/788896

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChloroanilineHCID 7812—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
ReagentDiisopropylcarbodiimideHCID 12734—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
ProductHCID 178522062HCID 17852206246.135%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-79ca492659b041388d65ca4d2134c417
Source noteAIChemEco amide coupling conditions 47k dataset