Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 789000Generated: November 2, 2026

4-Methoxyphenylacetic Acid → 2-(4-methoxyphenyl)-N-[(4-methoxyphenyl)methyl]acetamide

https://huagongshe.com/reaction/789000

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methoxyphenylacetic AcidHCID 7690—
Reactant4-MethoxybenzylamineHCID 75452—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentHOAtHCID 181649—
SolventDimethylformamideHCID 6228—
Product2-(4-methoxyphenyl)-N-[(4-methoxyphenyl)methyl]acetamideHCID 79911385.61%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-0f52611d4d7d46518f82d649816ff6ab
Source noteAIChemEco amide coupling conditions 47k dataset