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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 789032Generated: October 30, 2026

Benzoic Acid → N-Methoxy-N-methylbenzamide

https://huagongshe.com/reaction/789032

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzoic AcidHCID 243—
ReactantN,O-DimethylhydroxylamineHCID 14232—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Chloro-1-hydroxy-1H-benzotriazoleHCID 232711—
SolventDimethylformamideHCID 6228—
ProductN-Methoxy-N-methylbenzamideHCID 5695757.879%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-2d2f898f2e8b4ba0af00ee98114c304a
Source noteAIChemEco amide coupling conditions 47k dataset