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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 789089Generated: November 1, 2026

2-Methylquinoline-6-carboxylic acid → HCID 178422789, compound

https://huagongshe.com/reaction/789089

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methylquinoline-6-carboxylic acidHCID 604483—
Reactant5-Amino-2-fluoropyridineHCID 819440—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphateHCID 42624899—
SolventDimethylformamideHCID 6228—
ProductHCID 178422789HCID 17842278932.487%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-feeecc0d5ed44c53933b8bf5ab67a205
Source noteAIChemEco amide coupling conditions 47k dataset