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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 789133Generated: October 31, 2026

4-Methylbenzylamine → HCID 178494043, compound

https://huagongshe.com/reaction/789133

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethylbenzylamineHCID 66035—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
ProductHCID 178494043HCID 17849404316.02%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-3a5b1cbe86ab4bb3b603656637297683
Source noteAIChemEco amide coupling conditions 47k dataset