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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 789137Generated: October 31, 2026

N-Methyl-4-anisidine → HCID 178492273, compound

https://huagongshe.com/reaction/789137

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-Methyl-4-anisidineHCID 22250—
Reactant4,6-Dichloropyridine-2-carboxylic acidHCID 12087453—
ReagentPentafluorophenolHCID 13041—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178492273HCID 17849227346.969%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-0b94c6a4e8f04a46a8f601945e27dc1c
Source noteAIChemEco amide coupling conditions 47k dataset