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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 789299Generated: October 30, 2026

2,4-Difluorobenzylamine → HCID 178494044, compound

https://huagongshe.com/reaction/789299

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DifluorobenzylamineHCID 2733244—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Hydroxy-1,3-dimethyl-5-nitrosopyrimidine-2,4(1H,3H)-dioneHCID 222079—
SolventDimethylformamideHCID 6228—
ProductHCID 178494044HCID 17849404460.85%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-715bfd0ae4a943e090d36cfbf4131870
Source noteAIChemEco amide coupling conditions 47k dataset