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HRID78930

反应详情

EQUATION

反应方程式

HRID 78930 的结构方程式

REACTANTS

反应物

2
结构：COc1ccc(CN)cc1
HCID75452

4-Methoxybenzylamine

C8H11NO

结构：c1ccc(C(c2ccccc2)[C@H]2C[C@H]3O[C@H]3CO2)cc1
HCID86605348

未命名化合物

PRODUCTS

生成物

1
结构：COc1ccc(CN[C@H]2C[C@H](C(c3ccccc3)c3ccccc3)OC[C@H]2O)cc1
HCID66631546

未命名化合物

PROCEDURE

实验过程

(1S,4R,6R)-4-benzhydryl-3,7-dioxa-bicyclo[4.1.0]heptane 28d (0.02 g, 0.075 mmol) was reacted with p-methoxy-benzylamine (0.21 g, 1.50 mmol) (Procedure E) to yield (3S,4S,6R)-6-benzhydryl-4-(4-methoxy-benzylamino)-tetrahydropyran-3-ol, (+)-29g, 0.029 (94%, [α]D=(+)65, c=1, MeOH). The 1HNMR and 13CNMR were identical with (3R,4R,6S)-6-benzhydryl-4-(4-methoxy-benzylamino)-tetrahydropyran-3-ol.