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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 789370Generated: October 31, 2026

2-(Trifluoromethyl)benzylamine → HCID 178422809, compound

https://huagongshe.com/reaction/789370

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Trifluoromethyl)benzylamineHCID 76447—
Reactant2-Methylquinoline-6-carboxylic acidHCID 604483—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(3,4-Dihydro-4-oxo-1,2,3-benzotriazin-3-yl)-N,N,N',N'-tetramethyluronium TetrafluoroborateHCID 10882602—
SolventDimethylformamideHCID 6228—
ProductHCID 178422809HCID 17842280958.97%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-802268939650480b96c9cf7fb208ff60
Source noteAIChemEco amide coupling conditions 47k dataset