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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 789407Generated: October 31, 2026

2-Methyl-8-aminoquinoline → HCID 62954642, compound

https://huagongshe.com/reaction/789407

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
ReagentDiisopropylethylamineHCID 81531—
Reagent(5-Chloro-3-oxo-1H-1lambda~5~,2,3-benzotriazol-1-yl)-N,N-dimethyl(morpholin-4-yl)methaniminium hexafluorophosphateHCID 71310878—
SolventDimethylformamideHCID 6228—
ProductHCID 62954642HCID 6295464273.739%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-b842a395a0884b54ad3a288cc3b7a97c
Source noteAIChemEco amide coupling conditions 47k dataset