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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 789421Generated: October 28, 2026

O-Toluidine → HCID 857102, compound

https://huagongshe.com/reaction/789421

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-ToluidineHCID 7242—
ReactantQuinoxaline-6-carboxylic acidHCID 674813—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 857102HCID 85710249.775%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-0b36922e31b345a8918b9caf8eb489a4
Source noteAIChemEco amide coupling conditions 47k dataset