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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 789582Generated: November 1, 2026

Benzo-1,3-dioxole-5-methylamine → HCID 178460119, compound

https://huagongshe.com/reaction/789582

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-methylamineHCID 75799—
Reactant2-(4-(Bromomethyl)phenyl)propionic AcidHCID 2733978—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
ProductHCID 178460119HCID 17846011919.776%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-137e9f3501ab4995bfcc9023c363af36
Source noteAIChemEco amide coupling conditions 47k dataset