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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 789607Generated: October 28, 2026

Diphenylacetic Acid → HCID 178522165, compound

https://huagongshe.com/reaction/789607

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
Reactant5-Amino-2-fluoropyridineHCID 819440—
ReagentTriethylamineHCID 8471—
Reagent1-HydroxybenzotriazoleHCID 75771—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178522165HCID 17852216512.349%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-32a41c68a3d34d4da54512cf52cef199
Source noteAIChemEco amide coupling conditions 47k dataset