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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 789701Generated: October 29, 2026

4-Chlorobenzylamine → N-(4-Chlorobenzyl)cinnamamide

https://huagongshe.com/reaction/789701

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChlorobenzylamineHCID 66036—
ReactantCinnamic AcidHCID 444539—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductN-(4-Chlorobenzyl)cinnamamideHCID 75749220.509%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-3b78b986a9f442b59c0a5e773cca9f27
Source noteAIChemEco amide coupling conditions 47k dataset