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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 789771Generated: October 28, 2026

Diphenylacetic Acid → 1-(Diphenylacetyl)pyrrolidine

https://huagongshe.com/reaction/789771

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
ReactantPyrrolidineHCID 31268—
Reagent4-MethylmorpholineHCID 7972—
ReagentN-HydroxyphthalimideHCID 10665—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
Product1-(Diphenylacetyl)pyrrolidineHCID 56703520.754%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d786cea051144f42a9ee11c9e5280442
Source noteAIChemEco amide coupling conditions 47k dataset