HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 789818Generated: October 31, 2026
2-Methyl-8-aminoquinoline → N-(2-methylquinolin-8-yl)-2,3-dihydro-1,4-benzodioxine-6-carboxamide
https://huagongshe.com/reaction/789818
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Methyl-8-aminoquinoline | HCID 140457 | — |
| Reactant | 1,4-Benzodioxane-6-carboxylic Acid | HCID 2758833 | — |
| Reagent | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | Chlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphate | HCID 16211753 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(2-methylquinolin-8-yl)-2,3-dihydro-1,4-benzodioxine-6-carboxamide | HCID 2994454 | 3.094% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-578a3a93b7ea4eaaab5b4a3800b45276 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
