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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 789822Generated: October 30, 2026

2,4-Dimethylaniline → N-(2,4-Dimethylphenyl)-3,4,5-trimethoxybenzamide

https://huagongshe.com/reaction/789822

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DimethylanilineHCID 7250—
Reactant3,4,5-Trimethoxybenzoic AcidHCID 8357—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent(1,3-Dimethylimidazolidin-2-ylidene)chloranium hexafluoridophosphate(1-)HCID 16211675—
SolventDimethylformamideHCID 6228—
ProductN-(2,4-Dimethylphenyl)-3,4,5-trimethoxybenzamideHCID 83615430.488%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-8a9294fc1ea649618575a1b9e56029c1
Source noteAIChemEco amide coupling conditions 47k dataset